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Homo sapiens
36 Downloadable Samples
Affymetrix Human Gene 1.0 ST Array (hugene10st)
Description
This study addresses long-term effects of clinically relevant regimens of radiation in human glioma stem cells. Our investigations reveal a strikingly diverse spectrum of changes in cell behavior, gene expression patterns and tumor-propagating capacities evoked by radiation in different types of glioma stem cells. Evidence is provided that degree of cellular plasticity but not the propensity to self-renew is an important factor influencing radiation-induced changes in the tumor-propagating capacity of glioma stem cells. Gene expression analyses indicate that paralell transcriptomic responses to radiation underlie similarity of clinically relevant cellular outcomes such as the ability to promote tumor growth after radiation. Our findings underscore the importance of longitudinal characterizations of molecular and cellular responses evoked by cytotoxic treatrments in glioma stem cells.
Publication Title
Diversity of Clinically Relevant Outcomes Resulting from Hypofractionated Radiation in Human Glioma Stem Cells Mirrors Distinct Patterns of Transcriptomic Changes.
Sample Metadata Fields
Treatment
View Samples- Drosophila melanogaster
- 27 Downloadable Samples
Illumina HiSeq 2500
Description
No description.
Publication Title
No associated publication
Sample Metadata Fields
Sex, Specimen part, Cell line, Treatment
View Samples- Homo sapiens
- 16 Downloadable Samples
- Affymetrix Human Genome U133A 2.0 Array (hgu133a2)
Description
Study of the gene expression of T24 bladder cancer cells in response to hypericin-mediated photodynamic therapy in the absence or presence of the p38 MAPK inhibitor PD169316
Publication Title
Molecular effectors and modulators of hypericin-mediated cell death in bladder cancer cells.
Sample Metadata Fields
Specimen part, Cell line, Compound
View Samples- Homo sapiens
- 6 Downloadable Samples
- Illumina HiSeq 4000
Description
We propose a microfluidic strategy to generate abundant brain organoids and further explore neurogenesis in fetal brain exposed to ethanol.
Publication Title
No associated publication
Sample Metadata Fields
Sex, Specimen part, Disease, Cell line, Treatment
View Samples
SRP097584- Mus musculus
- 6 Downloadable Samples
- Illumina HiSeq 2500
Description
T cell lymphoma
Publication Title
PD-1 is a haploinsufficient suppressor of T cell lymphomagenesis.
Sample Metadata Fields
Sex, Specimen part, Cell line
View Samples- Mus musculus
- 2 Downloadable Samples
- Affymetrix Murine Genome U74A Version 2 Array (mgu74av2)
Description
P19 differentiating cells were spread a two densities and mRNA from the two densities were compared
Publication Title
No associated publication
Sample Metadata Fields
Cell line
View Samples- Drosophila melanogaster
- 1 Downloadable Sample
- Illumina HiSeq 2500
Description
Grapevines are easy to be attacked by Erysiphe necator, so it is significant to uncover why Chinese wild Vitis pseudoreticulata has strong resistance to such a common fungi, which can provide guidance for breeding disease resistance grapevine varieties. This project is aimed to unravel the defense mechanism of Chinese wild Vitis pseudoreticulata to Erysiphe necator on posttranscriptional level mediated by microRNAs. To profile the microRNA expression affected by Erysiphe necator infection and identify microRNAs relative to powdery mildew resistance, two sRNA libraries were constructed from inoculated and non-inoculated grapevine leaves for small RNA high throughput sequencing.
Publication Title
No associated publication
Sample Metadata Fields
Sex, Specimen part, Cell line, Treatment
View Samples- Mus musculus
- 6 Downloadable Samples
- Affymetrix Mouse Genome 430A 2.0 Array (mouse430a2)
Description
We hybridzed cRNA from epididymal white adipose tissue collected at ZT18 of control animals and TSR animals (TSR: these mice were sleep restricted for 6 hours every day by gentle handling for 5 consecutive days and killed on the last day at ZT18)
Publication Title
No associated publication
Sample Metadata Fields
Specimen part
View Samples- Mus musculus
- 185 Downloadable Samples
- Illumina HiSeq 2500
Description
To test the "one-neuron-one-receptor" rule of olfactory receptor expression, we sequenced the transcriptomes of single olfactory sensory neurons from the main olfactory epithelium of adult (1 to 3 months) and newborn mice (postnatal day 4 to 10).
Publication Title
No associated publication
Sample Metadata Fields
Sex, Specimen part, Cell line
View Samples- Homo sapiens
- 18 Downloadable Samples
- Illumina HiSeq 2000
Description
We report the biological activity of a Py-Im polyamide targeted to the sequence 5'-WGWWCW-3', which is found in a subset of ARE half-sites. This molecule reduces the growth of enzalutamide-resistant LREX' cells, both in vitro and in vivo. Gene expression changes associated with polyamide treatment in both settings are deposited here.
Publication Title
No associated publication
Sample Metadata Fields
Sex, Specimen part, Cell line
View Samples