Analysis of miRNA-targeted cellular NMD substrates in HeLa cell. The hypothesis tested in the present study was that endogenous NMD substrates containing long 3' untranslated region may targeted for miRNA. Results provide important information expanding the roles of miRISC in the posttranscriptional regulation of gene expression: a new cross-talk between miRNA-mediated gene silencing and NMD.
microRNA/Argonaute 2 regulates nonsense-mediated messenger RNA decay.
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View SamplesAnalysis of gene expression change of normal cells, human fore skin fibroblast (HFFs) upon over-expression of c-Myc
Oncogene-induced senescence mediated by c-Myc requires USP10 dependent deubiquitination and stabilization of p14ARF.
Cell line
View SamplesTranscriptome was performed to reveal the gene expression change in mouse thalamic LGN and MGB after visual deprivation throughing one-week dark exposure from postnatal day 21 to 28 day.
No associated publication
Sex, Specimen part
View SamplesAnalysis of the molecular mechanism through which Rh2 promotes cancer cell apoptosis at the transcriptome level.
No associated publication
Sex, Specimen part
View SamplesTranscriptomic sequencing of human gastric cancer cell line (AGS) upon citral treatment
No associated publication
Sex, Specimen part, Disease, Cell line
View SamplesVEGF and VEGFB Play Balancing Roles in Adipose Differentiation, Gene Expression and Function
No associated publication
Sex, Specimen part, Cell line
View Samplesgene expression study on brain and lung under Dip2a regulation to better understand the role of Dip2a gene during mice brain and lung development.
Large genomic fragment deletions and insertions in mouse using CRISPR/Cas9.
Sex, Specimen part, Cell line
View SamplescMyc is a master regulator of transcription in growing cells. Here, we used microarray to study global transcriptomic expression of cMyc knockdown HT1080 cells to investigate cMyc- regulated gene expression.
cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions.
Specimen part, Cell line
View SamplesSuperior frontal gyrus grey and white matter
Unique transcriptome patterns of the white and grey matter corroborate structural and functional heterogeneity in the human frontal lobe.
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View Sampleshuman Transcriptomehuman Transcriptomehuman Transcriptomehuman Transcriptomehuman Transcriptome
No associated publication
Sex, Age, Specimen part
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