Comparative analysis can provide important insights into complex biological systems. As demonstrated in the accompanying paper, Translating Ribosome Affinity Purification (TRAP), permits comprehensive studies of translated mRNAs in genetically defined cell populations following physiological perturbations.
Application of a translational profiling approach for the comparative analysis of CNS cell types.
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View SamplesThe cellular heterogeneity of the brain confounds efforts to elucidate the biological properties of distinct neuronal populations.
No associated publication
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View SamplesThe cellular heterogeneity of the brain confounds efforts to elucidate the biological properties of distinct neuronal populations.
A translational profiling approach for the molecular characterization of CNS cell types.
No sample metadata fields
View SamplesThe cellular heterogeneity of the brain confounds efforts to elucidate the biological properties of distinct neuronal populations.
No associated publication
No sample metadata fields
View SamplesThe cellular heterogeneity of the brain confounds efforts to elucidate the biological properties of distinct neuronal populations.
A translational profiling approach for the molecular characterization of CNS cell types.
No sample metadata fields
View SamplesThe cellular heterogeneity of the brain confounds efforts to elucidate the biological properties of distinct neuronal populations.
A translational profiling approach for the molecular characterization of CNS cell types.
No sample metadata fields
View SamplesHair follicle (HF) regeneration begins when communication between quiescent epithelial stem cells (SCs) and underlying mesenchymal dermal papillae (DP) generates sufficient activating cues to overcome repressive BMP signals from surrounding niche cells. We uncovered a hitherto unrecognized DP transmitter, TGF2, which activates Smad2/3 transiently in HFSCs concomitant with entry into tissue regeneration.
Paracrine TGF-β signaling counterbalances BMP-mediated repression in hair follicle stem cell activation.
Sex, Specimen part
View SamplesJournal : Blood. 2009 Jul 9;114(2):469-77. Epub 2009 May 13.
Endothelial deletion of hypoxia-inducible factor-2alpha (HIF-2alpha) alters vascular function and tumor angiogenesis.
Specimen part
View SamplesThis SuperSeries is composed of the SubSeries listed below.
Histone H3 lysine 9 di-methylation as an epigenetic signature of the interferon response.
Specimen part, Treatment
View SamplesDifferent allergens induce different immune responses
Molecular profiling of contact dermatitis skin identifies allergen-dependent differences in immune response.
Sex, Subject
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