We use single cell RNA-seq method to analysis the transcriptional heterogeneity in squamous cell carcinoma of urinary bladder. The single cell sequencing approach is based on the method of single-cell tagged reverse transcription (STRT).
No associated publication
Sex, Age, Specimen part
View Sampleswe characterized the small RNA content of exosomes derived from gastric cancer cell lines by deep sequencing
No associated publication
No sample metadata fields
View SamplesThis study was to identify gene expression profile change associated withß-estradiol treatment in osteosarcoma cells by high-throughput RNA sequencing
No associated publication
Sex, Specimen part, Cell line
View SamplesCelecoxib is an inhibitor of cyclooxygenase-2-incuced lung squamous cell carcinoma (LSQCC). The study aims to provide novel insight into celecoxib’s chemoprevention
No associated publication
Sex, Specimen part, Cell line
View SamplesDifferential gene expression analysis of parental and sub-lines of melanoma cell line resistant to F5 CTL lymphocyte
Molecular mechanism of MART-1+/A*0201+ human melanoma resistance to specific CTL-killing despite functional tumor-CTL interaction.
Cell line
View SamplesEffect of injury and Pseudomonas aeruginosa inoculation in Drosophila melanogaster
Involvement of skeletal muscle gene regulatory network in susceptibility to wound infection following trauma.
Sex, Time
View SamplesNotch signaling critically controls cell fate decisions in mammals, both during embryogenesis and in adults. In the skeleton, Notch suppresses osteoblast differentiation and sustains bone marrow mesenchymal progenitors during postnatal life. Stabilizing mutations of Notch2 cause the Hajdu-Cheney syndrome characterized by early onset osteoporosis in humans, but the mechanism whereby Notch inhibits bone accretion is not fully understood.To gain further insights about the mechanism we performed RNA-seq experiments with the doxycycline-inducible NICD2-ST2 cells with or without doxycycline treatment for 24 hrs.
No associated publication
Sex, Specimen part, Cell line, Treatment
View SamplesWhole transcript expression analysis was performed on liver biopsy from wild mice,DEN model mice and cell-treated mice(2 mice per group)
Transplantation of periportal vessel stem cells promotes liver injury repair in cirrhotic mice
Age, Specimen part
View SamplesMacrophages from RA synovial fluids were compared to primary human monocyte-derived macrophages.
Interferon-γ Represses M2 Gene Expression in Human Macrophages by Disassembling Enhancers Bound by the Transcription Factor MAF.
Specimen part, Disease stage, Subject
View SamplesGene expression analysis of freshly isolated CD14+ human monocytes and monocytes cultured in the presence or absence of interferon (IFN) -gamma for 24 h and then stimulated with Pam3Cys, a Toll-like receptor (TLR) 2 ligand, for 6 h. Results provide insight into mechanisms by which IFN-gamma reprograms early macrophage differentiation and subsequent response to TLR ligands.
Integrated regulation of Toll-like receptor responses by Notch and interferon-gamma pathways.
No sample metadata fields
View Samples