Analysis of expression of periglomerular cells from laser microdissection (LMD) samples
No associated publication
Specimen part
View SamplesTo transcriptionally profile necklace olfactory sensory neurons.
No associated publication
Sex, Specimen part, Cell line
View SamplesNo description.
No associated publication
Sex, Age, Specimen part, Cell line
View SamplesDuring embryogenesis the heart forms as a linear tube that then undergoes multiple simultaneous morphogenetic events to obtain its mature shape. To understand the gene regulatory networks (GRNs) driving this phase of heart development, during which many congenital heart disease malformations likely arise, we conducted an RNA-seq timecourse in zebrafish from 30 hpf to 72 hpf and identified 5861 genes with altered expression. We clustered the genes by temporal expression pattern, identified transcription factor binding motifs enriched in each cluster, and generated a model GRN for the major gene batteries in heart morphogenesis.
No associated publication
No sample metadata fields
View SamplesThis project aims to identify genes that are differentially expressed by premyelinating oligodendrocytes in the absence of transcription factor EB (TFEB). Premyelinating oligodendrocytes were acutely purified by immunopanning approach from P12 Olig2-Cre; TFEB F/+ or P12 Olig2-Cre; TFEB F/F mouse brains. Bulk sequencing were performed with 4 biological replicates per genotype.
No associated publication
Sex, Specimen part, Cell line
View SamplesMicroarrays were used to identify the differentially expressed genes in the hippocampus of control and Noonan syndrom mice at basal state and in response to 4AP-Bic stimulation (10 min). Functional analysis was performed to determine the biological significance of the data.
No associated publication
Specimen part
View SamplesBackground. Nuclear factor I-A (NFI-A), a phylogenetically conserved transcription/replication protein, plays a crucial role in mouse brain development. Previous studies showed that disruption of the Nfia gene in mice leads to perinatal lethality, corpus callosum agenesis, and hydrocephalus.
Gene expression analysis of nuclear factor I-A deficient mice indicates delayed brain maturation.
No sample metadata fields
View SamplesNormal human colorectal mucosa was sampled at points along the colon.
Map of differential transcript expression in the normal human large intestine.
Specimen part
View Samples<p/>
No associated publication
No sample metadata fields
View SamplesHuman NK cells were sorted into CD56dim and CD56bright NK cell subpopulations. In order to define characteristics of both populations gene profiling was performed using Affymetrix arrays U133a and U133B.
Gene and protein characteristics reflect functional diversity of CD56dim and CD56bright NK cells.
Specimen part
View Samples