Apicomplexan protozoans of Eimeria spp. cause coccidiosis, one of the most economically relevant parasitic diseases in chickens. The lack of a complete understanding of molecular mechanisms in host-parasite interaction limits the development of effective control measures. In the present study, RNA sequencing (RNA-seq) was applied to investigate the host mRNA profiles of the cecal mucosa and its contents collected at day 5 post Eimeria maxima (EM) infection.
No associated publication
Sex, Specimen part, Cell line
View SamplesTranscriptome of connective tissue of swine affected and non-affected with scrotal hernia
No associated publication
Sex, Age, Specimen part, Disease
View SamplesThe study of the compond PIP-RBPJ-1 function on neural stem cell. Synthetic DNA-binding inhibitors capable of gaining precise control over neurogenesis factors could obviate the current clinical barriers associated with small molecule use in regenerative medicine. Here, we show the design and bio-efficacy of a synthetic ligand PIP-RBPJ-1 to cause promoter-specific suppression of neurogenesis-associated HES1, and its downstream genes. Furthermore, PIP-RBPJ-1 alone could alter the neural system-associated notch signaling factors and remarkably induce neurogenesis with an efficiency that is comparable to a conventional approach. Here is one day treatment of the PIP-RBPJ-1 on neural stem cells.
No associated publication
Specimen part
View SamplesThis SuperSeries is composed of the SubSeries listed below.
A genomic predictor of response and survival following taxane-anthracycline chemotherapy for invasive breast cancer.
Specimen part, Disease stage
View SamplesValidation dataset of 298 ER-positive patients treated with tamoxifen for 5 years.
No associated publication
Specimen part, Subject
View SamplesPURPOSE: To develop a predictive test for response and survival following neoadjuvant taxane-anthracycline chemotherapy for HER2-negative invasive breast cancer.
A genomic predictor of response and survival following taxane-anthracycline chemotherapy for invasive breast cancer.
Specimen part, Disease stage
View SamplesPURPOSE: To develop an index capable of detecting and quantifying the extent of liver RNA contamination in liver biopsies of metastatic breast cancer
No associated publication
Specimen part
View SamplesPURPOSE: To develop a predictive test for response and survival following neoadjuvant taxane-anthracycline chemotherapy for HER2-negative invasive breast cancer.
A genomic predictor of response and survival following taxane-anthracycline chemotherapy for invasive breast cancer.
Specimen part, Disease stage
View SamplesMolecular and genomic analysis of microscopic quantities of tumor from formalin-fixed and paraffin-embedded (FFPE) biopsies has many unique challenges. Here we evaluated the feasibility of obtaining transcriptome-wide RNA expression to measure prognostic classifiers from diagnostic prostate needle core biopsies.
Application of a Clinical Whole-Transcriptome Assay for Staging and Prognosis of Prostate Cancer Diagnosed in Needle Core Biopsy Specimens.
Specimen part, Subject
View SamplesTo test the hypothesis that a genomic classifier (GC) would predict biochemical failure (BF) and distant metastasis (DM) in men receiving radiation therapy (RT) after radical prostatectomy (RP).
The Landscape of Prognostic Outlier Genes in High-Risk Prostate Cancer.
Age
View Samples