This SuperSeries is composed of the SubSeries listed below.
MicroRNAs reprogram normal fibroblasts into cancer-associated fibroblasts in ovarian cancer.
Specimen part, Time
View SamplesCampare the difference between pairwise NOF and coCAF tissues for three patients
MicroRNAs reprogram normal fibroblasts into cancer-associated fibroblasts in ovarian cancer.
Specimen part, Time
View SamplesCompare the difference between pairwise aNOF and CAF samples for two patients
MicroRNAs reprogram normal fibroblasts into cancer-associated fibroblasts in ovarian cancer.
Specimen part
View SamplesCompare the difference between pairwise NOF and iCAF (2d) tissues for one patient
MicroRNAs reprogram normal fibroblasts into cancer-associated fibroblasts in ovarian cancer.
Specimen part, Time
View SamplesHere we propose the direct conversion of human somatic cells into naive induced pluripotent cells (niPSC). Dataset: 7 expanded niPSC lines (4 from BJ cells, 1 from HFF-1, 1 from WI38, 1from IMR90), 1 freshly-isolated primary colonies of niPSC from BJ, 1 established naive embryonic line H9, 1 primed induced pluripotent cell line (from BJ), 1 sample of BJ fibroblasts, 1 sample of WI38 fibroblasts, 1 sample IMR90 fibroblasts.
Direct generation of human naive induced pluripotent stem cells from somatic cells in microfluidics.
No sample metadata fields
View SamplesThe developmental potential of human pluripotent stem cells suggests that they can produce disease-relevant cell types for biomedical research. However, substantial variation has been reported among pluripotent cell lines, which could affect their utility and clinical safety. Such cell-line specific differences must be better understood before one can confidently use embryonic stem (ES) or induced pluripotent stem (iPS) cells in translational research. Towards this goal we have established genome-wide reference maps of DNA methylation and gene expression for 20 previously derived human ES lines and 12 human iPS cell lines, and we have measured the in vitro differentiation propensity of these cell lines. This resource enabled us to assess the epigenetic and transcriptional similarity of ES and iPS cells and to predict the differentiation efficiency of individual cell lines. The combination of assays yields a scorecard for quick and comprehensive characterization of pluripotent cell lines.
Reference Maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines.
Sex, Cell line
View SamplesChildren with acute measles were admitted to the University Teaching Hospital in Lusaka, Zambia. Peripheral blood was collected at hospital entry, discharge and 1-month follow-up. Control samples were also collected from uninfected children. All children were HIV negative.
Gene expression changes in peripheral blood mononuclear cells during measles virus infection.
No sample metadata fields
View SamplesHuman CD14+ monocytes were isolated and grown in GM-CSF and IL-4 for six days. The cells were then infected with measles virus, Chicago-1 strain, and RNA was isolated at 3, 6, 12, and 24 hours post-infection.
Gene expression patterns in dendritic cells infected with measles virus compared with other pathogens.
No sample metadata fields
View SamplesThis SuperSeries is composed of the SubSeries listed below.
The Gene Expression Barcode: leveraging public data repositories to begin cataloging the human and murine transcriptomes.
Treatment
View SamplesWe used yeast RNA to estimate background binding for each probe on the human U133 plus 2.0 array.
The Gene Expression Barcode: leveraging public data repositories to begin cataloging the human and murine transcriptomes.
Treatment
View Samples