The overall goal and objective is to study the degree to which PAX3-FKHR accounts for differences between ARMS and ERMS by expressing a construct (termed P3FK/ER) consisting of PAX3-FKHR joined to the estrogen receptor ligand binding domain in an ERMS cell culture system.
Identification of PAX3-FKHR-regulated genes differentially expressed between alveolar and embryonal rhabdomyosarcoma: focus on MYCN as a biologically relevant target.
Cell line
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Genomic and transcriptomic comparison of post-radiation versus sporadic sarcomas.
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Genomic and transcriptomic comparison of post-radiation versus sporadic sarcomas.
Sex, Age, Specimen part, Disease, Disease stage
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