Wild type and transgenic msi1-tap1 plants were grown and gene expression was compared at two time points at the age of 8 days.
Regulation of flowering time by Arabidopsis MSI1.
Age, Time
View SamplesPlants were grown in growth chambers at 70% humidity and daily cycles of 16 h light and 8 h darkness at 21 C. Plant material used for the experiments was pooled from 12 plants. Stage I and stage II samples contained complete flower buds (stage I) or flowers (stage II). For stage III samples only siliques without withering flower organs were harvested. About 10% of the tissues for each sample were cleared and analyzed by microscopy to ensure that homogenous developmental stages were harvested. The entire experiment was performed twice providing independent biological replicates.
Transcriptional programs of early reproductive stages in Arabidopsis.
Specimen part
View SamplesComparison of Arabidopsis mutants lacking CAF-1 subunits
Functional genomic analysis of CAF-1 mutants in Arabidopsis thaliana.
Age, Time
View SamplesRNA was labeled and hybridized to ATH1 arrays.
Arabidopsis RETINOBLASTOMA-RELATED is required for stem cell maintenance, cell differentiation, and lateral organ production.
Specimen part, Compound
View Samplestranscriptomic analysis in rosette leaves of bru1-2 and WT(Col) plants (24-day-old)
Ectopic gene expression and organogenesis in Arabidopsis mutants missing BRU1 required for genome maintenance.
Age, Specimen part
View SamplesBackground: Renal cell carcinoma (RCC) is characterized by a number of diverse molecular aberrations that differ among individuals. Recent approaches to molecularly classify RCC were based on clinical, pathological as well as on single molecular parameters. As a consequence, gene expression patterns reflecting the sum of genetic aberrations in individual tumors may not have been recognized. In an attempt to uncover such molecular features in RCC, we used a novel, unbiased and integrative approach.
Integrative genome-wide expression profiling identifies three distinct molecular subgroups of renal cell carcinoma with different patient outcome.
Sex, Specimen part, Disease, Disease stage, Cell line
View SamplesLateral root initiation was used as a model system to study the mechanisms behind auxin-induced cell division. Genome-wide transcriptional changes were monitored during the early steps of lateral root initiation. Inclusion of the dominant auxin signaling mutant solitary root1 (slr1) identified genes involved in lateral root initiation that act downstream of the AUX/IAA signaling pathway. Interestingly, key components of the cell cycle machinery were strongly defective in slr1, suggesting a direct link between AUX/IAA signaling and core cell cycle regulation. However, induction of the cell cycle in the mutant background by overexpression of the D-type cyclin (CYCD3;1) was able to trigger complete rounds of cell division in the pericycle that did not result in lateral root formation. Therefore, lateral root initiation can only take place when cell cycle activation is accompanied by cell fate respecification of pericycle cells. The microarray data also yielded evidence for the existence of both negative and positive feedback mechanisms that regulate auxin homeostasis and signal transduction in the pericycle, thereby fine-tuning the process of lateral root initiation.
Cell cycle progression in the pericycle is not sufficient for SOLITARY ROOT/IAA14-mediated lateral root initiation in Arabidopsis thaliana.
No sample metadata fields
View SamplesRNA from etiolated seedlings, light-treated seedlings, leaves and flowers was hybridized to ATH1 and AGRONOMICS1 arrays.
AGRONOMICS1: a new resource for Arabidopsis transcriptome profiling.
Age, Specimen part
View SamplesThis SuperSeries is composed of the SubSeries listed below.
Complementary strand microRNAs mediate acquisition of metastatic potential in colonic adenocarcinoma.
Sex
View SamplesCompariosn of mRNA and miRNA profile in colon cancer
Complementary strand microRNAs mediate acquisition of metastatic potential in colonic adenocarcinoma.
Sex
View Samples