A set of changes is identified in the transcription profile associated with the long-term, but not the acute, response to radiation exposure. The study was performed in vivo using zebrafish.
Long-term effects of ionizing radiation on gene expression in a zebrafish model.
Age, Specimen part, Treatment
View SamplesIn an attempt to gain insight into the mechanism whereby irradiated cells influence the outcome of DSB repair in their non-irradiated neighbors, we performed whole genome expression profiling.
Co-culturing with High-Charge and Energy Particle Irradiated Cells Increases Mutagenic Joining of Enzymatically Induced DNA Double-Strand Breaks in Nonirradiated Cells.
Cell line
View SamplesTransgelin was the top-ranked marker of metastatic potential identified in the comparison of node-positive colorectal cancer (CRC) versus node-negative CRC in our previous study. Transgelin is localized in the nucleus of cultured CRC cells and microRNA-mediated knockdown of TAGLN (the gene encoding transgelin) expression modulates the expression of genes involved in the epithelial-to-mesenchymal transition.
Transgelin increases metastatic potential of colorectal cancer cells in vivo and alters expression of genes involved in cell motility.
Specimen part, Cell line
View SamplesTriplicate experiments from T98G cells under asynchronously growing, and growth arrest by serum deprivation and contact inhibition.
A common set of gene regulatory networks links metabolism and growth inhibition.
No sample metadata fields
View SamplesThis SuperSeries is composed of the SubSeries listed below.
Regulation of transcriptional elongation in pluripotency and cell differentiation by the PHD-finger protein Phf5a.
Specimen part, Cell line
View SamplesPhf5a regulates transcription elongation in mouse embryonic stem cells (ESCs), through regulation of the Paf1 complex.
Regulation of transcriptional elongation in pluripotency and cell differentiation by the PHD-finger protein Phf5a.
Specimen part, Cell line
View Samples