Right ventricular samples were serially acquired during surgical repair of ventricular septal defect. Expression profiling revealed three patterns of gene expression: (1) increased expression above control levels within one hour of cardioplegic arrest, with further amplification during early reperfusion; (2) increased expression limited to the reperfusion phase; and (3) reduced expression during reperfusion.
Early gene expression profiles during intraoperative myocardial ischemia-reperfusion in cardiac surgery.
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View SamplesThe endogenous peptide Apelin is crucial for maintaining heart function in pressure overload and aging
Impaired heart contractility in Apelin gene-deficient mice associated with aging and pressure overload.
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