Expression data from SKOV3.ip cells by knockdown RAD51-AS1 expression.

GSE89374

Homo sapiens

6 Downloadable Samples

Affymetrix Human Transcriptome Array 2.0 (hta20)

Submitter Supplied Information

Description

Long non-coding RNAs (lncRNA) have been shown to play crucial roles in tumorigenesis. Little is known about lncRNA RAD51-AS1 in diseases. Here, we investigated the role of RAD51-AS1 in Epithelial ovarian cancer. Silencing RAD51-AS1 inhibited proliferation through cell cycle arrest and promotion in apoptosis, both in vitro and in vivo. But the mechanism of RAD51-AS1 downstream regulation remains unclear.

PubMed ID

28667302

Publication Title

E2F1-regulated long non-coding RNA RAD51-AS1 promotes cell cycle progression, inhibits apoptosis and predicts poor prognosis in epithelial ovarian cancer.

Total Samples

Submitter’s Institution

Obstetrics and Gynecology Hospital of Fudan University

Authors

Zhang X, Liu G, Qiu J, Zhang N, Ding J, Hua K

Source Repository

Gene Expression Omnibus (GEO)

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