The transcription factor Gli3 promotes differentiation from double positive to CD4 single positive thymocyte by repression of Shh

GSE87499

Mus musculus

18 Downloadable Samples

Affymetrix Mouse Gene 2.0 ST Array (mogene20st)

Submitter Supplied Information

Description

We used Affymetrix microarrays to understand the genome wide differences in Wildtype and Gli3 mutant (Gli3+/- and Gli3-/-) (n=2) embryonic day 18.5 DP CD69-, DP CD69+ and SP4 thymocytes.

PubMed ID

29361554

Publication Title

Gli3 in fetal thymic epithelial cells promotes thymocyte positive selection and differentiation by repression of <i>Shh</i>.

Total Samples

Submitter’s Institution

UCL

Authors

Solanki A, Yanez DC, Ross S, Lau CI, Papaioannou E, Li J, Saldaña JI, Crompton T

Source Repository

Gene Expression Omnibus (GEO)

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