Effect of JAK blockade on IFNa response in CD4+ T cells in vitro

GSE84565

Mus musculus

14 Downloadable Samples

Affymetrix Mouse Gene 1.0 ST Array (mogene10st)

Submitter Supplied Information

Description

CD4+ T cells respond robustly to type 1 interferons which signal through JAK1 and TYK2. Here we analyzed the effects of a panel of JAK inhibitors on the IFNa transcriptional response in activated CD4+ T cells in vitro.

PubMed ID

27516546

Publication Title

Network pharmacology of JAK inhibitors.

Total Samples

Submitter’s Institution

Harvard Medical School

Authors

Moodley D, Yoshida H, Mostafavi S, Asinovski N, Ortiz-Lopez A, Symanowicz P, Telliez JB, Hegen M, Clark JD, Mathis D, Benoist C

Source Repository

Gene Expression Omnibus (GEO)

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