Different Preference of Degradome in Invasion versus Angiogenesis

We hypothesized altered expression of Proteases in calls capable of physiological invasion vs angiogenesis. We analyzed trophoblasts isolated from first trimester placenta that are invasive, and placental endothelial cells, that gave a high angiogenic potential. We found different expression levels of most proteases.

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Ghaffari-Tabrizi-Wizsy N, Cvitic S, Tam-Amersdorfer C, Bilban M, Majali-Martinez A, Schramke K, Desoye G, Hiden U