The role of AR-associated factors in androgen signaling

Prostate cancer is the most common cancer in men and AR downstream signalings promote prostate cancer cell proliferation. We identified androgen-regulated genes, CTBP2, FOXP1 and RUNX1. These factors interact with AR ligand dependently.

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Takayama K, Suzuki T, Fujimura T, Urano T, Takahashi S, Homma Y, Inoue S