Expression profiles of HepG2 cells treated with low-, high-dose of acetaminophen and solvent control

GSE53216

Homo sapiens

35 Downloadable Samples

Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Submitter Supplied Information

Description

The transcriptomics changes induced in the human liver cell line HepG2 by low and high doses of acetaminophen and solvent controls after treatment for 4 time points (12h, 24h, 48h and 72h)

PubMed ID

25704631

Publication Title

Increased mitochondrial ROS formation by acetaminophen in human hepatic cells is associated with gene expression changes suggesting disruption of the mitochondrial electron transport chain.

Total Samples

Submitter’s Institution

Maastricht University

Authors

Jiang J, Briedé JJ, Jennen DG, Van Summeren A, Saritas-Brauers K, Schaart G, Kleinjans JC, de Kok TM

Source Repository

Gene Expression Omnibus (GEO)

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