Hoxb1 mutant mRNA levels in rhombomere 4 at E10.5

GSE5126

Mus musculus

6 Downloadable Samples

Affymetrix Mouse Expression 430A Array (moe430a)

Submitter Supplied Information

Description

Hoxb1 is required for proper specification of rhombomere 4 and the facial motor neurons. This study analyzed gene expression in the corresponding hindbrain segment of E10.5 mutant embryos. Several genetic pathways were found altered, including transcription factors such as Phox2b, Gata3, Nkx2-2 and Nkx6-1.

PubMed ID

16890163

Publication Title

Reversal of Hox1 gene subfunctionalization in the mouse.

Total Samples

Submitter’s Institution

University of Utah

Authors

Tvrdik P, Capecchi MR

Source Repository

Gene Expression Omnibus (GEO)

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