Expression analysis of LM8 osteosarcoma cells overexpressing human Prolyl Hydroxylase Domain Protein-4 (PHD4) and LM8 control cells

GSE49680

Mus musculus

2 Downloadable Samples

Affymetrix Mouse Expression 430A Array (moe430a)

Submitter Supplied Information

Description

PHD4 regulates the expression of Hypxia-inducible Factor 2 (HIF-2) alpha in LM8 osteosarcoma cells. PHD4 overexpression inhibits the growth of experimental tumor in syngenic mice but stimulates angiogenesis via Transforming Growth-Factor (TGF)-alpha.

PubMed ID

24048703

Publication Title

PHD4 stimulates tumor angiogenesis in osteosarcoma cells via TGF-α.

Total Samples

Submitter’s Institution

TU Dresden

Authors

Klotzsche-von Ameln A, Prade I, Grosser M, Kettelhake A, Rezaei M, Chavakis T, Flamme I, Wielockx B, Breier G

Source Repository

Gene Expression Omnibus (GEO)

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