Relapse from nicotine abstinence increases the pacemaking frequency of cholinergic habenular neurons

Build and Download Custom Datasets

refine.bio helps you build ready-to-use datasets with normalized transcriptome data from all of the world’s genetic databases.

GSE43164

Mus musculus

6 Downloadable Samples

Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Submitter Supplied Information

Description

The discovery of genetic variants in the CHRNA5-CHRNA3-CHRNB4 gene cluster associated with heavy smoking and higher relapse risk has led to the identification of the midbrain habenula- interpeduncular axis as a critical relay circuit in the control of nicotine addiction

PubMed ID

24082085

Publication Title

Reexposure to nicotine during withdrawal increases the pacemaking activity of cholinergic habenular neurons.

Total Samples

Submitter’s Institution

Washington University

Authors

Görlich A, Antolin-Fontes B, Ables JL, Frahm S, Slimak MA, Dougherty JD, Ibañez-Tallon I

Source Repository

Gene Expression Omnibus (GEO)

No rows found