TGF-beta 1 effect on primary bovine aortic endothelial cells

GSE42932

Bos taurus

6 Downloadable Samples

Affymetrix Bovine Genome Array (bovine)

Submitter Supplied Information

Description

Analysis of primary bovine aortic endothelial cells treated for 24 hours with TGF-beta 1 5 ng/ml. TGF-beta 1 has been shown to induce endothelial-to-mesenchymal transition (EndoMT) and to be implicated in differentiation of endothelial cells into smooth muscle-like cells as occurred in vascular neointimal formation.

PubMed ID

23572561

Publication Title

LOXL4 is induced by transforming growth factor β1 through Smad and JunB/Fra2 and contributes to vascular matrix remodeling.

Total Samples

Submitter’s Institution

CNB, CSIC

Authors

Busnadiego O, González-Santamaría J, Lagares D, Guinea-Viniegra J, Pichol-Thievend C, Muller L, Rodríguez-Pascual F

Source Repository

Gene Expression Omnibus (GEO)

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