Expression data of inducible stable cell lines overexpressing Ero1alpha WT and Ero1alpha C104A/C131A

GSE40601

Homo sapiens

12 Downloadable Samples

Affymetrix Human Gene 1.0 ST Array (hugene10st)

Submitter Supplied Information

Description

The overall cellular response to oxidative stress generated by Ero1 in the lumen of the mammalian endoplasmic reticulum (ER) is poorly characterized. Here, we investigate the effects of overexpressing a hyperactive mutant (C104A/C131A) of Ero1.

PubMed ID

23027870

Publication Title

Hyperactivity of the Ero1α oxidase elicits endoplasmic reticulum stress but no broad antioxidant response.

Total Samples

Submitter’s Institution

University of Copenhagen

Authors

Hansen HG, Schmidt JD, Søltoft CL, Ramming T, Geertz-Hansen HM, Christensen B, Sørensen ES, Juncker AS, Appenzeller-Herzog C, Ellgaard L

Source Repository

Gene Expression Omnibus (GEO)

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