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Accession IconGSE39354

Expression profiling of human prostate VCaP and LNCaP cancer cells after silencing ERG or ETV1, respectively

Organism Icon Homo sapiens
Sample Icon 22 Downloadable Samples
Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

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Description
Chromosomal rearrangements involving ETS factors, ERG and ETV1, occur frequently in prostate cancer. We here examine human prostate cancer cells control VCaP and LNCaP cells with ERG- or ETV1-silenced VCaP or LNCaP cells, respectively, in hormone deprived and stimulated conditions.
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24
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VCaP-siControl-DHT-B
prostate
vcap
transfected with sicontrol were grown in androgen deprived serum for 2 days and then in the presence of 10nm dht
VCaP-siERG-EtOH-C
prostate
vcap
transfected with sierg were grown in androgen deprived serum for 2 days and then in the presence of etoh
VCaP-siControl-EtOH-B
prostate
vcap
transfected with sicontrol were grown in androgen deprived serum for 2 days and then in the presence of etoh
VCaP-siControl-DHT-A
prostate
vcap
transfected with sicontrol were grown in androgen deprived serum for 2 days and then in the presence of 10nm dht
LNCaP-shETV1-DHT-B
prostate
lncap
transfected with shetv1 were grown in androgen deprived serum for 2 days and then in the presence of 10nm dht
VCaP-siERG-DHT-A
prostate
vcap
transfected with sierg were grown in androgen deprived serum for 2 days and then in the presence of 10nm dht
VCaP-siERG-DHT-C
prostate
vcap
transfected with sierg were grown in androgen deprived serum for 2 days and then in the presence of 10nm dht
LNCaP-shControl-DHT-A
prostate
lncap
transfected with sicontrol were grown in androgen deprived serum for 2 days and then in the presence of 10nm dht
LNCaP-shControl-DHT-B
prostate
lncap
transfected with sicontrol were grown in androgen deprived serum for 2 days and then in the presence of 10nm dht
VCaP-siControl-DHT-C
prostate
vcap
transfected with sicontrol were grown in androgen deprived serum for 2 days and then in the presence of 10nm dht
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