Intratumoral diversity in Follicular lymphoma

GSE38816

Homo sapiens

16 Downloadable Samples

Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Submitter Supplied Information

Description

Follicular lymphoma (FL) shows heterogenous expression of the cell surface B-cell marker, CD20. In order to investigate whether this heterogeneity also marks underlying transcriptional heterogeneity, we sorted tumor B-cells from 8 FL specimens based upon their intermediate or high expression of CD20 and transcriptionally profiled them.

PubMed ID

23297126

Publication Title

Hierarchy in somatic mutations arising during genomic evolution and progression of follicular lymphoma.

Total Samples

Submitter’s Institution

MD Anderson Cancer Center

Authors

Green MR, Gentles AJ, Nair RV, Irish JM, Kihira S, Liu CL, Kela I, Hopmans ES, Myklebust JH, Ji H, Plevritis SK, Levy R, Alizadeh AA

Source Repository

Gene Expression Omnibus (GEO)

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