Hepatic gene expression in streptozotocin-induced diabetic mice fed a phloridzin diet

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GSE38138

Mus musculus

20 Downloadable Samples

Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Submitter Supplied Information

Description

Phloridzin is a dihydrochalcone typically contained in apples. A diet containing 0.5 % phloridzin significantly improves hyperglycemia but not hypoinsulinemia and tissue lipid peroxidation in streptozotocin (STZ)-induced diabetic mice after 14 days. The phloridzin diet has no effect on the alteration of hepatic gene expression in STZ-induced diabetic mice.

PubMed ID

19413312

Publication Title

Dietary phloridzin reduces blood glucose levels and reverses Sglt1 expression in the small intestine in streptozotocin-induced diabetic mice.

Total Samples

Submitter’s Institution

Food Research Institute, National Agriculture and Food Research Organization

Authors

Masumoto S, Akimoto Y, Oike H, Kobori M

Source Repository

Gene Expression Omnibus (GEO)

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