Human colon epithelial cells treated with Clostridium difficile Toxins A and B

GSE29008

Homo sapiens

19 Downloadable Samples

Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Submitter Supplied Information

Description

Toxin A and B from Clostridium difficile are the primary virulence factors in Clostridium difficile disease. The changes in gene transcription of human colon epithelial cells were investigated in vitro in order to better understand the many effects of both toxins.

PubMed ID

22225989

Publication Title

Systems analysis of the transcriptional response of human ileocecal epithelial cells to Clostridium difficile toxins and effects on cell cycle control.

Total Samples

Submitter’s Institution

University of Virginia

Authors

D'Auria KM, Donato GM, Gray MC, Kolling GL, Warren CA, Cave LM, Solga MD, Lannigan JA, Papin JA, Hewlett EL

Source Repository

Gene Expression Omnibus (GEO)

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