Expression data from lateral nasal gland of male B6, 129/Sv and Cyp2g1-null mice

GSE26056

Mus musculus

9 Downloadable Samples

Affymetrix Mouse Genome 430A 2.0 Array (mouse430a2)

Submitter Supplied Information

Description

In male Cyp2g1-null mice, the lateral nasal gland, one of the largest anterior glands in the nasal cavity, was found to be protected from acetaminophen toxicity. The goal of this study was to identify the genes that are involved in the mechanisms, especially those genes functional in drug metabolism, clearance and post-activation events.

PubMed ID

21252290

Publication Title

A novel defensive mechanism against acetaminophen toxicity in the mouse lateral nasal gland: role of CYP2A5-mediated regulation of testosterone homeostasis and salivary androgen-binding protein expression.

Total Samples

Submitter’s Institution

Wadsworth Center

Authors

Zhou X, Wei Y, Xie F, Laukaitis CM, Karn RC, Kluetzman K, Gu J, Zhang QY, Roberts DW, Ding X

Source Repository

Gene Expression Omnibus (GEO)

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