Effect of Valproic Acid on Endothelial Cells

GSE23909

Homo sapiens

10 Downloadable Samples

Affymetrix Human Gene 1.0 ST Array (hugene10st)

Submitter Supplied Information

Description

Valproic acid (VPA) is a short-chain fatty acid used in the treatment of epilepsy and also considered to be an epigenetic modifier by functioning as a histone deacetylase (HDAC)-inhibitor. The aim of this study was to search for gene altered by VPA in human endothelial cells.

PubMed ID

22363677

Publication Title

Role of histone acetylation in the stimulatory effect of valproic acid on vascular endothelial tissue-type plasminogen activator expression.

Total Samples

Submitter’s Institution

institute of medicine

Authors

Larsson P, Ulfhammer E, Magnusson M, Bergh N, Lunke S, El-Osta A, Medcalf RL, Svensson PA, Karlsson L, Jern S

Source Repository

Gene Expression Omnibus (GEO)