Hepatic transcriptomic alterations for 1,2-bis(tribromophenoxy)ethane (BTBPE) (Firemaster 680) after 5-day exposure in rats

To identify liver transcripts differentially expressed due to treatment with 1,2-bis(tribromophenoxy)ethane (BTBPE) (Firemaster 680), we collected RNA from male Harlan Sprague Dawley rats exposed to 0, 0.07, 0.69, 6.88, 68 or 680 mg/kg BTBPE, 5 days after exposure for animals 7 weeks of age. These samples were interrogated with the Affymetrix Rat Genome 230 2.0 GeneChip array.

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Shockley KR, Cora MC, Malarkey DE, Jackson-Humbles D, Vallant M, Collins BJ, Mutlu E, Robinson VG, Waidyanatha S, Zmarowski A, Machesky N, Richey J, Harbo S, Cheng E, Patton K, Sparrow B, Dunnick JK