Ago2 or Dicer knockdown effects on mRNA levels in HeLa

GSE13638

Homo sapiens

11 Downloadable Samples

Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Submitter Supplied Information

Description

Analysis of mRNA changes in HeLa cells following Ago2 or Dicer depletion. Dicer, a cytoplasmic RNase III, generates the mature form of small RNAs including microRNA. Ago2 is a component of an effector complex of microRNA.

PubMed ID

19135890

Publication Title

Posttranscriptional crossregulation between Drosha and DGCR8.

Total Samples

Submitter’s Institution

Seoul National University

Authors

Han J, Pedersen JS, Kwon SC, Belair CD, Kim YK, Yeom KH, Yang WY, Haussler D, Blelloch R, Kim VN

Source Repository

Gene Expression Omnibus (GEO)

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