Cardiomyocytes microarray

GSE107385

Homo sapiens

5 Downloadable Samples

Affymetrix Human Gene 2.0 ST Array (hugene20st)

Submitter Supplied Information

Description

we employed DNA microarray platform to compare the gene expression patterns in primary human cardiomyocytes treated with trastuzumab (50g/ml), trastuzumab (50g/ml) plus pertuzumab (50g/ml), T-DM1 (10 g/ml), or control (no treatment).

PubMed ID

29464058

Publication Title

Type IIB DNA topoisomerase is downregulated by trastuzumab and doxorubicin to synergize cardiotoxicity.

Total Samples

Submitter’s Institution

FDA

Authors

Jiang J, Mohan N, Endo Y, Shen Y, Wu WJ

Source Repository

Gene Expression Omnibus (GEO)

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