Genome-wide analysis of gene expression by IFN in Transformed HMEC (Epithelial/non-CSC, Mesenchymal/CSC)

Triple Negative Breast Cancer (TNBC), the deadliest form of this disease, lacks a targeted therapy. TNBC tumors that fail to respond to chemotherapy are characterized by a repressed Interferon/Signal Transducer and Activator of Transcription (IFN/STAT) gene signature and are often enriched for Cancer Stem Cells (CSCs).

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